But they shook off the dust from their feet against them, and came to Iconium. (Acts 13:51 NKJV)
The Lord had been working powerfully through Paul and Barnabass. As they preached the gospel many responded and were converted. The word of God was spreading through the entire region. Yet immediately following this work of God came opposition. There were religious and legalistic Jews that came in and began to cause division and undermine the work. Paul and Barnabass stood there ground, but eventually they moved on. The outward demonstration in there moving on was shaking off the dust from their garments. Jesus told His disciples on their short term missionary journey that if they were not received to shake off the dust from their garments.(Mark 6). As they shook off the dust they moved on and ministered where they were received.
Sometimes within ministry God can be working mightily. But this work will not always be received. It can even be opposed or criticized. The devil often likes to start little fires in different places all at one time. This creates diversions,distractions,and often discouragement. What are you supposed to do? Do you try and put out everyone? You can try.But will come to discover you cannot please everyone. Be more concerned with pleasing God. There are days however, when all you can do is simply "shake off the dust". The comments,the actions,whatever it might be that would want to cling to you and rob you of your joy in the Lord.